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Before Nebraska
Isabel Kiser played high school soccer at Lincoln Southwest for head coach Thomas Nettleton and club ball at Gretna Elite Academy for head coach Jon Brezenski. Lincoln Southwest was state champion in 2024 and 2025 and state runner-up in 2023. Kiser was on the Lincoln Journal Star Super-State second team and the LJS All-State team in 2025. In 2024, she was a second-team Class A All-State team member. Kiser earned an All-State honorable mention as a freshman in 2023.

Personal
Kiser intends to major in nutrition and health sciences at Nebraska.